Testosterone can be found in various preparations, esterified variants, as well as forms. Pure un-esterified testosterone has an extremely short half-life – as a matter of fact, too short for use. It cannot be conveniently and comfortably administered. This is why ester bonds of various types have been created to form diverse esterified Testosterone variants to allow for ease of administration as well as for the purpose of prolonging its half-life to lengths that are both more practical and useable. When an ester bond is added to the testosterone molecule, it makes the best potential maximization of medical as well as non-medical use. It is possible to create or find virtually an endless amount of esterified types and variants of testosterone. There are three major and popular types that are famous both in the world of medicine and the anabolic steroid using circles, which this is article is focused on.
Starting with the most popular one, they include:
- Testosterone Enanthate
- Testosterone Cypionate
- Testosterone Propionate
Testosterone Enanthate is probably both the most widely used and most popular esterified variant of Testosterone. This can largely be attributed to its more extended half-life and prolonged window of release that enables more convenient injection and administration procedures to be carried out. Since Testosterone Enanthate’s half-life is about 7 – 10 days, its protocol conveniently allows for injection once or twice per week, thus it differs from Testosterone Propionate that calls for a protocol of once every other day injection. As such, its longer half- life makes it more suitable for medical and TRT use, but not for performance enhancing application, especially for those who are not comfortable with engaging in frequent injections.
Although Testosterone Cypionate differs from Testosterone Enanthate chemically, it is considered to be virtually its equivalent. Its half-life is similar, albeit is a bit longer (around 12 days and 10 days for each respectively). Another key difference between the two testosterones is their origins. While Testosterone Enanthate is mainly an international product (with universal origins), Testosterone Cypionate is usually an American product. There is no difference between the two in terms of half-lives. Besides, they are almost equally popular among anabolic steroid users. However, between the two, Testosterone Enanthate enjoys more popularity.
The similarity between these two esterified testosterone variants is so much such that they can be swapped within a circle without any problems at all. Testosterone Cypionate offers the same ease and convenience of infrequent use, just the same way as Testosterone Enanthate and any additional long-estered compound.
Testosterone Propionate occupies the third positions among the most popular types of Testosterone esters after Testosterone Enanthate and Testosterone Cypionate, although this esterified form of Testosterone was the very first one to be produced. It prolongs the half-life of the Testosterone in the body to about 4.5 days. This is far shorter than the two esterified variants of testosterone discussed earlier on. Thus, in order to maintain unwavering blood plasma levels of the hormone, there is need for a considerably more frequent injection procedure than the other ester variations (no less than every other day injections). This is what makes it less popular among a good number of users who have preference for less frequent injections. But this should not be construed to mean that Testosterone Propionate is an unpopular anabolic steroid. That is not the case whatsoever. It is the favourite for a niche group of anabolic steroid users who prefer it more than the others. As a matter of fact, its uncomfortable and inconvenient injections and administration schedule is what makes Testosterone Propionate occupy the third position in terms of popularity.
So basically, the differences among the three lies in how long the user needs to run each compound for maximum effect, as well as the injection frequency due to the ester.